Prime time for α-synuclein

被引：40

作者：

Gitler, Aaron D. ^{[1
]}

Shorter, James ^{[1
]}

机构：

[1] Whitehead Inst Biomed Res, Cambridge, MA 02142 USA

来源：

JOURNAL OF NEUROSCIENCE | 2007年 / 27卷 / 10期

关键词：

D O I：

10.1523/JNEUROSCI.0094-07.2007

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：2433 / 2434

页数：2

共 12 条

[1] Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system [J].

Abeliovich, A ;

Schmitz, Y ;

Fariñas, I ;

Choi-Lundberg, D ;

Ho, WH ;

Castillo, PE ;

Shinsky, N ;

Verdugo, JMG ;

Armanini, M ;

Ryan, A ;

Hynes, M ;

Phillips, H ;

Sulzer, D ;

Rosenthal, A .

NEURON, 2000, 25 (01) :239-252

[2]

Cabin DE, 2002, J NEUROSCI, V22, P8797

[3] α-synuclein cooperates with CSPα in preventing neurodegeneration [J].

Chandra, S ;

Gallardo, G ;

Fernández-Chacón, R ;

Schlüter, OM ;

Südhof, TC .

CELL, 2005, 123 (03) :383-396

[4] Double-knockout mice for α- and β-synucleins:: Effect on synaptic functions [J].

Chandra, S ;

Fornai, F ;

Kwon, HB ;

Yazdani, U ;

Atasoy, D ;

Liu, XR ;

Hammer, RE ;

Battaglia, G ;

German, DC ;

Castillo, PE ;

Südhof, TC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (41) :14966-14971

[5] α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models [J].

Cooper, Antony A. ;

Gitler, Aaron D. ;

Cashikar, Anil ;

Haynes, Cole M. ;

Hill, Kathryn J. ;

Bhullar, Bhupinder ;

Liu, Kangning ;

Xu, Kexiang ;

Strathearn, Katherine E. ;

Liu, Fang ;

Cao, Songsong ;

Caldwell, Kim A. ;

Caldwell, Guy A. ;

Marsischky, Gerald ;

Kolodner, Richard D. ;

LaBaer, Joshua ;

Rochet, Jean-Christophe ;

Bonini, Nancy M. ;

Lindquist, Susan .

SCIENCE, 2006, 313 (5785) :324-328

[6] SNAREs - engines for membrane fusion [J].

Jahn, Reinhard ;

Scheller, Richard H. .

NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2006, 7 (09) :631-643

[7] Defective membrane interactions of familial Parkinson's disease mutant A30P α-synuclein [J].

Jo, EJ ;

Fuller, N ;

Rand, RP ;

St George-Hyslop, P ;

Fraser, PE .

JOURNAL OF MOLECULAR BIOLOGY, 2002, 315 (04) :799-807

[8] α-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis [J].

Larsen, Kristin E. ;

Schmitz, Yvonne ;

Troyer, Matthew D. ;

Mosharov, Eugene ;

Dietrich, Paula ;

Quazi, Abrar Z. ;

Savalle, Magali ;

Nemani, Venu ;

Chaudhry, Farrukh A. ;

Edwards, Robert H. ;

Stefanis, Leonidas ;

Sulzer, David .

JOURNAL OF NEUROSCIENCE, 2006, 26 (46) :11915-11922

[9] Mechanisms of Parkinson's disease linked to pathological α-synuclein:: New targets for drug discovery [J].

Lee, Virginia M. -Y. ;

Trojanowski, John Q. .

NEURON, 2006, 52 (01) :33-38

[10] Molecular pathophysiology of Parkinson's disease [J].

Moore, DJ ;

West, AB ;

Dawson, VL ;

Dawson, TM .

ANNUAL REVIEW OF NEUROSCIENCE, 2005, 28 :57-87

← 1 2 →