Synthesis and reactions of (E)- and (Z)-1,3-dibromo-2-methoxypropene

被引：5

作者：

Edvardsen, KR

Benneche, T

Tius, MA

机构：

[1] Univ Oslo, Dept Chem, N-0315 Oslo, Norway

[2] Univ Hawaii Manoa, Dept Chem, Honolulu, HI 96822 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 10期

关键词：

D O I：

10.1021/jo991822l

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(Z)-1,3-Dibromo-2-methoxypropene is prepared in 90% yield by dehydrohalogenation of 1,2,3-tribromo-2-methoxypropane with diisopropylamine in dichloromethane. The E-isomer can be obtained as the only product in almost quantitative yield by UV irradiation of the Z-isomer. Nucleophilic displacement reactions of the allylic bromide and palladium-catalyzed coupling reactions of the vinylic bromide in (E)- and (Z)-1,3-dwibromo-2-methoxypropene have been studied.

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收藏

页码：3085 / 3089

页数：5

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