Of man in mice

被引:3
作者
Athanikar, JN [1 ]
Morrish, TA
Moran, JV
机构
[1] Univ Michigan, Sch Med, Dept Human Genet, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Sch Med, Dept Internal Med, Ann Arbor, MI 48109 USA
关键词
D O I
10.1038/ng1043
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
L1 retrotransposition is ongoing, and has dramatically affected the evolution and structure of mammalian genomes. Despite their impact on the genome, little is known about when, where or how frequently L1s retrotranspose in vivo. The establishment of a mouse model of human L1 retrotransposition is a major step toward answering these questions.
引用
收藏
页码:562 / 563
页数:2
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