Sudden Unexpected Death in Epilepsy (SUDEP): Update and Reflections

被引:85
作者
Nashef, Lina [1 ]
Ryvlin, Philippe [2 ,3 ,4 ]
机构
[1] Kings Coll Hosp London, Dept Neurol, London SE5 9RS, England
[2] Hosp Civils Lyon, INSERM, U821, Dept Funct Neurol & Epileptol, Lyon, France
[3] Hosp Civils Lyon, INSERM, U821,CTRS IDEE, Inst Epilepsies Enfant & Adolescent, Lyon, France
[4] Univ Lyon 1, F-69365 Lyon, France
关键词
Epilepsy; SUDEP; Definitions; AEDs; Mortemus; Supervision; RISK-FACTORS; IDIOPATHIC EPILEPSY; UNEXPLAINED DEATH; SEROTONIN; SEIZURES; DEFINITIONS; FLUOXETINE; RATS; LAMOTRIGINE; PERSPECTIVE;
D O I
10.1016/j.ncl.2009.08.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This article addresses aspects of sudden unexpected death in epilepsy, reflecting on current knowledge and questions that need answers to quantify, monitor, and reduce risk. A brief overview is followed by a discussion of definitions, drug treatment, genetic susceptibility, mechanisms in relation to seizure monitoring units and supervision, with some suggestions for the way forward.
引用
收藏
页码:1063 / +
页数:13
相关论文
共 51 条
[1]   SUDEP: Overview of definitions and review of incidence data [J].
Annegers, JF ;
Coan, SP .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 1999, 8 (06) :347-352
[2]   United States perspective on definitions and classifications [J].
Annegers, JF .
EPILEPSIA, 1997, 38 :S9-S12
[3]   Lamotrigine in idiopathic epilepsy - increased risk of cardiac death? [J].
Aurlien, D. ;
Tauboll, E. ;
Gjerstad, L. .
ACTA NEUROLOGICA SCANDINAVICA, 2007, 115 (03) :199-203
[4]   New SCN5A mutation in a SUDEP victim with idiopathic epilepsy [J].
Aurlien, Dag ;
Leren, Trond P. ;
Tauboll, Erik ;
Gjerstad, Leif .
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY, 2009, 18 (02) :158-160
[5]   Ictal hypoxemia in localization-related epilepsy: analysis of incidence, severity and risk factors [J].
Bateman, Lisa M. ;
Li, Chin-Shang ;
Seyal, Masud .
BRAIN, 2008, 131 :3239-3245
[6]  
BATEMAN LM, 2008, BRAIN 12, V131, P199
[7]   Sudden unexplained death in epilepsy: An intracranially monitored case [J].
Bird, JM ;
Dembny, KAT ;
Sandeman, D ;
Butler, S .
EPILEPSIA, 1997, 38 :S52-S56
[8]  
Camfield Peter, 2005, Semin Pediatr Neurol, V12, P10, DOI 10.1016/j.spen.2004.11.005
[9]   Anticonvulsant doses of carbamazepine increase hippocampal extracellular serotonin in genetically epilepsy-prone rats: Dose response relationships [J].
Dailey, JW ;
Reith, MEA ;
Yan, QS ;
Li, MY ;
Jobe, PC .
NEUROSCIENCE LETTERS, 1997, 227 (01) :13-16
[10]  
*DOCT DEL, 1854, TERM TRAIT EP, P165