Hepatitis disease diagnosis using a new hybrid system based on feature selection (FS) and artificial immune recognition system with fuzzy resource allocation

This paper presents a novel method for diagnosis of hepatitis disease. The proposed method is based on a hybrid method that uses feature selection (FS) and artificial immune recognition system (AIRS) with fuzzy resource allocation mechanism. AIRS has showed an effective performance on several problems such as machine learning benchmark problems and medical classification problems like breast cancer, diabets, liver disorders classification. By hybridizing FS and AIRS with fuzzy resource allocation mechanism, a method is obtained to solve this diagnosis problem via classifying. The robustness of this method with regard to sampling variations is examined using a cross-validation method. We used hepatitis disease dataset which is taken from UCI machine learning repository. We obtained a classification accuracy of 92.59%, which is the highest one reached so far. The classification accuracy was obtained via 10-fold cross validation. The obtained classification accuracy of our system was 92.59% and it was very promising with regard to the other classification applications in literature for this problem. Also, sensitivity, and specificity values for hepatitis disease dataset were obtained as 100 and 85%. (C) 2006 Elsevier Inc. All rights reserved.