Detection of West Nile virus sequences in cerebrospinal fluid

被引：79

作者：

Briese, T ^{[1
]}

Glass, WG

Lipkin, WI

机构：

[1] Univ Calif Irvine, Dept Neurol, Emerging Dis Lab, Irvine, CA 92697 USA

[2] Univ Calif Irvine, Dept Microbiol & Mol Genet, Irvine, CA 92697 USA

[3] Univ Calif Irvine, Dept Anat, Irvine, CA 92697 USA

[4] Univ Calif Irvine, Dept Neurobiol, Irvine, CA 92697 USA

来源：

LANCET | 2000年 / 355卷 / 9215期

关键词：

D O I：

10.1016/S0140-6736(00)02220-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have established a sensitive and specific real-time PCR method for detection of West Nile virus. Analysis of specimens obtained during the 1999 New York outbreak indicated the presence of viral sequences in cerebrospinal fluid of all of four individuals with fatal outcomes, and in only one of four who survived.

引用

页码：1614 / 1615

页数：2

共 5 条

[1] [Anonymous], 1997, MMWR Recomm Rep, V46, P1
[2] Centers for Disease Control and Prevention (CDC), 1999, MMWR Morb Mortal Wkly Rep, V48, P845
[3] KINETIC PCR ANALYSIS - REAL-TIME MONITORING OF DNA AMPLIFICATION REACTIONS
HIGUCHI, R
FOCKLER, C
DOLLINGER, G
WATSON, R
[J]. BIO-TECHNOLOGY, 1993, 11 (09): : 1026 - 1030
[4] Diagnosis of viral infections of the central nervous system: Clinical interpretation of PCR results
Jeffery, KJM
Read, SJ
Peto, TEA
MayonWhite, RT
Bangham, CRM
[J]. LANCET, 1997, 349 (9048) : 313 - 317
[5] ALLELIC DISCRIMINATION BY NICK-TRANSLATION PCR WITH FLUOROGENIC PROBES
LEE, LG
CONNELL, CR
BLOCH, W
[J]. NUCLEIC ACIDS RESEARCH, 1993, 21 (16) : 3761 - 3766

← 1 →