Laparoscopy-assisted and open living donor right hepatectomy: A comparative study of outcomes

被引:101
作者
Baker, Talia B. [1 ]
Jay, Colleen L. [1 ]
Ladner, Daniela P. [1 ]
Preczewski, Luke B. [1 ]
Clark, Lori [1 ]
Holl, Jane [2 ]
Abecassis, Michael M. [1 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Organ Transplantat, Chicago, IL 60611 USA
[2] Northwestern Univ, Feinberg Sch Med, Inst Healthcare Studies, Chicago, IL 60611 USA
关键词
LIVER-TRANSPLANTATION; SINGLE INSTITUTION; STRESS-RESPONSE; NEPHRECTOMY; DONATION; SURGERY; CLASSIFICATION; METAANALYSIS; RESECTIONS; ADULT;
D O I
10.1016/j.surg.2009.05.022
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background. Minimally invasive liver surgery is a rapidly advancing field with demonstrated applicability to living donation. In this paper, we compare the safety and efficacy of laparoscopy-assisted door right hepatectomy (LADRH) to open donor right hepatectomy (ODRH). Methods. We performed a retrospective, comparative analysis of 33 LADRH to the most recent 33 ODRH performed at our institution, evaluation donor complications, costs, and recipient outcomes. Results. Donor demographics including age, gender, body mass index (BMI), and vascular and biliary anomalies were comparable. Donor complication rates were equivalent for LADRH and ODRH. Donor operative times were shorter for LADRH (LADRH 265 minutes, ODRH 316, P < .001) even after adjusting for BMI. Blood loss and length of stay were comparable. Additionally, total hospitalization costs were equivalent (LADRH $1.00, P - 19). Higher operative supply costs for LADRH were balanced by higher time-based operative costs for ODRH resulting in no significant differences in total operative costs. Finally, there were no differences in graft size, recipient patient of graft survival, or recipient vascular or biliary complications. Conclusion. Our experience suggests that LADRH compares favorably with ODRH with equivalent safety, resource utilization, and effectiveness. We believer that LADRH provides potential physical and psychological benefits without an adverse effect on outcomes (Surgery 2009; 146: 817-25.)
引用
收藏
页码:817 / 825
页数:9
相关论文
共 24 条
[1]  
ABECASSIS M, 2001, CURR OPIN ORGAN TRAN, V6, P355
[2]   The metabolic and immune response to laparoscopic vs open liver resection [J].
Burpee, SE ;
Kurian, M ;
Murakame, Y ;
Benevides, S ;
Gagner, M .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2002, 16 (06) :899-904
[3]   Stress response to laparoscopic surgery - A review [J].
Buunen, M ;
Gholghesaei, M ;
Veldkamp, R ;
Meijer, DW ;
Bonjer, HJ ;
Bouvy, ND .
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, 2004, 18 (07) :1022-1028
[4]   DEFINITION AND CLASSIFICATION OF NEGATIVE OUTCOMES IN SOLID-ORGAN TRANSPLANTATION - APPLICATION IN LIVER-TRANSPLANTATION [J].
CLAVIEN, PA ;
CAMARGO, CA ;
CROXFORD, R ;
LANGER, B ;
LEVY, GA ;
GREIG, PD .
ANNALS OF SURGERY, 1994, 220 (02) :109-120
[5]   Classification of surgical complications - A new proposal with evaluation in a cohort of 6336 patients and results of a survey [J].
Dindo, D ;
Demartines, N ;
Clavien, PA .
ANNALS OF SURGERY, 2004, 240 (02) :205-213
[6]   Comparison of open and laparoscopic live donor nephrectomy [J].
Flowers, JL ;
Jacobs, S ;
Cho, E ;
Morton, A ;
Rosenberger, WF ;
Evans, D ;
Imbembo, AL ;
Bartlett, ST .
ANNALS OF SURGERY, 1997, 226 (04) :483-489
[7]   Donor morbidity after living donation for liver transplantation [J].
Ghobrial, Rafik M. ;
Freise, Chris E. ;
Trotter, James F. ;
Tong, Lan ;
Ojo, Akinlolu O. ;
Fair, Jeffrey H. ;
Fisher, Robert A. ;
Emond, Jean C. ;
Koffron, Alan J. ;
Pruett, Timothy L. ;
Olthoff, Kim M. .
GASTROENTEROLOGY, 2008, 135 (02) :468-476
[8]  
*HLTH RES SERV ADM, 2007, 2007 ANN REP US ORG
[9]   Laparoscopic-assisted right lobe donor hepatectomy [J].
Koffron, A. J. ;
Kung, R. ;
Baker, T. ;
Fryer, J. ;
Clark, L. ;
Abecassis, M. .
AMERICAN JOURNAL OF TRANSPLANTATION, 2006, 6 (10) :2522-2525
[10]   Laparoscopic liver surgery: Shifting the management of liver tumors [J].
Koffron, Alan ;
Geller, David ;
Gamblin, T. Clark ;
Abecassis, Michael .
HEPATOLOGY, 2006, 44 (06) :1694-1700