Cell cycle: On target with Myc

被引:71
作者
Zornig, M
Evan, GI
机构
[1] Biochem. of the Cell Nucleus Lab., Imp. Cancer Res. Fund Laboratories, London WC2A 3PX
关键词
D O I
10.1016/S0960-9822(02)70769-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent evidence indicates that the c-Myc proto-oncogene activates transcription of cdc25A. The Cdc25A protein phosphatase is required both for progression through mitosis and for Myc-induced apoptosis, making cdc25A the most attractive Myc target gene identified so far.
引用
收藏
页码:1553 / 1556
页数:4
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