Estimation of glucose diffusion coefficient in scleral tissue

被引：14

作者：

Bashkatov, AN ^{[1
]}

Genina, EA ^{[1
]}

Sinichkin, YP ^{[1
]}

Lakodina, NA ^{[1
]}

Kochubey, VI ^{[1
]}

Tuchin, VV ^{[1
]}

机构：

[1] Saratov State Univ, Saratov 410026, Russia

来源：

SARTOV FALL MEETING '99: OPTICAL TECHNOLOGIES IN BIOPHYSICS AND MEDICINE | 2000年 / 4001卷

关键词：

glucose; light scattering; sclera; diffusion coefficient;

D O I：

10.1117/12.381513

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Results of experimental and theoretical study of the optical properties of the eye sclera controlled by administration of osmotically active chemical, such as glucose, are presented. Glucose administration induces the diffusion of matter and as a result the equalization of the refractive indices of collagen fibrils and base material, and corresponding changes of transmittance spectra of scleral tissue. Transmittance spectra of the human scleral samples impregnated by glucose were measured. The significant increase of transmittance under action of osmotic liquid was observed. The diffusion coefficient of glucose within scleral tissue was estimated; the average value is 3.45.10(-6) +/- 4.59.10(-7) cm(2)/sec. The results are general and can be used to describe many other fibrous tissues impregnated by osmotically active chemical agents.

引用

页码：345 / 355

页数：5

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