Interfacing Live Cells with Nanocarbon Substrates

被引：254

作者：

Agarwal, Shuchi ^{[1
]}

Zhou, Xiaozhu ^{[2
]}

Ye, Feng ^{[1
]}

He, Qiyuan ^{[2
]}

Chen, George C. K. ^{[3
]}

Soo, Jianchow ^{[1
]}

Boey, Freddy ^{[2
]}

Zhang, Hua ^{[2
]}

Chen, Peng ^{[1
]}

机构：

[1] Nanyang Technol Univ, Sch Chem & Biomed Engn, Singapore 637457, Singapore

[2] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore

[3] Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore 639798, Singapore

来源：

LANGMUIR | 2010年 / 26卷 / 04期

关键词：

LAYER GRAPHENE OXIDE; CARBON; NANOTUBES; SCAFFOLDS; FILMS; BIOCOMPATIBILITY; NANOSCALE; REDUCTION;

D O I：

10.1021/la9048743

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nanocarbon materials, including single-walled carbon nanotubes (SWCNTs) and graphene, promise Various novel biomedical applications (e.g., nanoelectronic biosensing). In this Letter, we study the ability of SWCNT networks and reduced graphene oxide (rGO) films in interfacing several types of cells, Such as neuroendocrine PC12 cells, oligodendroglia cells, and osteoblasts. It was found that rGO is biocompatible with all these cell types, whereas the SWCNT network is inhibitory to the proliferation, viability, and neuritegenesis of PC12 cells, and the proliferation of osteoblasts. These observations could be attributed to the distinct nanotopographic features of these two kinds of nanocarbon substrates.

引用

页码：2244 / 2247

页数：4

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