A convenient large scale synthesis of O-benzylhydroxylamine

被引：5

作者：

Bonaccorsi, F

Giorgi, R

机构：

[1] Menarini Ricerche S.p.A, Medicinal Chemistry Department, 56122 S.Piero a Grado (PI)

来源：

SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 07期

关键词：

D O I：

10.1080/00397919708003349

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetically useful O-benzylhydroxylamine can be conveniently prepared in large scale by reaction of N-hydroxyphthalimide and benzyl chloride in phase transfer conditions, followed by acidic hydrolysis of N-benzyloxyphthalimide. The overall yield is over 65 %.

引用

页码：1143 / 1147

页数：5

共 5 条

[1] REACTION OF 2- AND 4-VINYLPYRIDINE WITH HYDROXYLAMINE, BENZYLOXYAMINE, AND PHTHALHYDRAZIDE [J].