The P1 component of the middle latency auditory potential may differentiate a brainstem subgroup of Alzheimer disease

被引：5

作者：

Green, JB

Burba, A

Freed, DM

Elder, WW

Xu, WC

机构：

[1] LOYOLA STRITCH UNIV,SCH MED,DEPT NEUROL,MAYWOOD,IL

[2] TEXAS TECH UNIV,HLTH SCI CTR,DEPT NEUROL,LUBBOCK,TX 79430

来源：

ALZHEIMER DISEASE & ASSOCIATED DISORDERS | 1997年 / 11卷 / 03期

关键词：

Alzheimer disease; black reflex; P1; component; subgroups;

D O I：

10.1097/00002093-199709000-00007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The P1 component of the middle latency auditory evoked potential (:MLAEP) was found to be absent in 47.5% of 101 patients with Alzheimer disease (AD). Lack of a P1 component recently has been associated with a more rapid decline in cognitive performance. The blink reflex (BR) was tested in 36 patients with probable AD and 17 elderly control subjects. All subjects also underwent pi recording. Patients lacking a P1 potential showed a significant increase in latency of the contralateral R2 response of the BR. The pi component and the R2 response may differentiate a subgroup of AD patients with involvement of the brainstem, especially the reticular formation.

引用

收藏

页码：153 / 157

页数：5

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