Ribosomal protein S1 induces a conformational change of the 30S ribosomal subunit

被引:5
作者
Agalarov, Sultan Ch. [1 ]
Kalinichenko, Artem A. [1 ]
Kommer, Aigar A. [1 ]
Spirin, Alexander S. [1 ]
机构
[1] Russian Acad Sci, Inst Prot Res, Pushchino 142290, Russia
关键词
ribosome; ribosomal protein S1; protein topography; tritium labeling;
D O I
10.1016/j.febslet.2006.11.036
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A comparative study of the 30S ribosomal subunit in the complex with protein Sl and the subunit depleted of this protein has been carried out by the hot tritium bombardment method. Differences in exposure of some ribosomal proteins within the 30S subunit depleted of S1 and within the 30S-S1 complex were found. It was concluded that protein S1 binds in the region of the neck of the 30S ribosomal subunit inducing a conformational change of its structure. (c) 2006 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:6797 / 6799
页数:3
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