Stability of extemporaneous norfloxacin suspension

被引：11

作者：

Boonme, P ^{[1
]}

Phadoongsombut, N ^{[1
]}

Phoomborplub, P ^{[1
]}

Viriyasom, S ^{[1
]}

机构：

[1] Prince Songkla Univ, Fac Pharmaceut Sci, Hat Yai 90112, Songkhla, Thailand

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 2000年 / 26卷 / 07期

关键词：

norfloxacin; stability; suspension;

D O I：

10.1081/DDC-100101298

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The stability of norfloxacin as extemporaneous suspensions compounded from two brands of film-coated tablets (formulas I and II) was studied. The vehicle consisted of tragacanth, saccharin sodium, sorbitol solutio, glycerin, paraben concentrate, peppermint spirit BP, purified water, and syrup USP. The final concentration of norfloxacin in the suspensions was 20 mg/ml. formulas I and II were chemically stable for 28 days when stored in amber glass bottles at ambient temperature; however, their physical characteristics were different.

引用

页码：777 / 779

页数：3

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