Economic evaluation of vaccination programs: The impact of herd-immunity

被引:195
作者
Brisson, M
Edmunds, WJ
机构
[1] Publ Hlth Lab Serv, Ctr Communicable Dis Surveillance, Immunisat Div, London NW9 5EQ, England
[2] City Univ London, Dept Econ, London EC1V 3HD, England
关键词
infectious diseases; externality; modeling; vaccination; dynamic models;
D O I
10.1177/0272989X02239651
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
The unique characteristic of vaccination is that it not only reduces the incidence of disease in those humanized but also indirectly protects nonvaccinated susceptibles against infection (produces herd-immunity). The bulk of economic evaluations of vaccination programs continue to use models that cannot take into account the indirect effects produced by herd-immunity. Here, the authors illustrate the importance of incorporating herd-immunity externalities when assessing the cost-effectiveness of vaccination programs. To do this, they compare 2 methods of estimating the benefits of routine mass vaccination: one that includes herd-immunity (dynamic approach) and one that does not (static approach). Finally, they use the results to clarify a number of misconceptions that are common in the literature concerning herd-immunity and dynamical effects produced by models.
引用
收藏
页码:76 / 82
页数:7
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