Binding of caffeine by a synthetic co-receptor

被引：20

作者：

Ballester, P ^{[1
]}

Barceló, MA

Costa, A

Deyà, PM

Morey, J

Orell, M

Hunter, CA

机构：

[1] Univ Illes Balears, Dept Quim, E-07071 Palma de Mallorca, Spain

[2] Univ Sheffield, Dept Chem, Sheffield S3 7HF, S Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 20期

关键词：

molecular recognition; macrocycles; cyclophanes; hydrogen bonding;

D O I：

10.1016/S0040-4039(00)00506-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new co-receptor macrobicyclophane for binding caffeine has been developed. The co-receptor binding sites are based on the hydrogen bonding abilities of secondary amides. H-1 NMR titrations demonstrate recognition of caffeine by formation of a 2:1 complex in CDCl3. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3849 / 3853

页数：5

共 18 条

[1] [2]CATENANE OR NOT [2]CATENANE [J].

ADAMS, H ;

CARVER, FJ ;

HUNTER, CA .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (08) :809-810

[2]

[Anonymous], 1987, Binding Constant

[3] Influence of remote intramolecular hydrogen bonds on the thermodynamics of molecular recognition of cis-1,3,5-cyclohexanetricarboxylic acid. [J].

Ballester, P ;

Costa, A ;

Deyà, PM ;

Vega, M ;

Morey, J ;

Deslongchamps, G .

TETRAHEDRON LETTERS, 1999, 40 (01) :171-174

[4] MOLECULAR RECOGNITION OF CIS-1,3,5-CYCLOHEXANE TRICARBOXYLIC-ACID [J].

BALLESTER, P ;

COSTA, A ;

DEYA, PM ;

GONZALEZ, JF ;

ROTGER, MC ;

DESLONGCHAMPS, G .

TETRAHEDRON LETTERS, 1994, 35 (22) :3813-3816

[5] PREORGANIZATION - FROM SOLVENTS TO SPHERANDS [J].

CRAM, DJ .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1986, 25 (12) :1039-1057

[6]

Eblinger F, 1998, ANGEW CHEM INT EDIT, V37, P826, DOI 10.1002/(SICI)1521-3773(19980403)37:6<826::AID-ANIE826>3.0.CO

[7]

2-Z

[8] SYNTHESIS AND STRUCTURE ELUCIDATION OF A NEW [2]-CATENANE [J].

HUNTER, CA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (13) :5303-5311

[9]

Job P, 1928, ANN CHIM FRANCE, V9, P113

[10] MULTISITE MOLECULAR RECEPTORS AND CO-SYSTEMS AMMONIUM CRYPTATES OF MACROTRICYCLIC STRUCTURES [J].

KOTZYBAHIBERT, F ;

LEHN, JM ;

VIERLING, P .

TETRAHEDRON LETTERS, 1980, 21 (10) :941-944

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