Kleine-Levin syndrome in a 14-year-old girl:: CSF hypocretin-l measurements

被引：21

作者：

Podesta, Claudio ^{[1
]}

Ferreras, Monica

Mozzi, Marcela

Bassetti, Claudio

Dauvilliers, Yves

Billiard, Michel

机构：

[1] FLENI, Sleep Lab, Dept Neurol, Buenos Aires, DF, Argentina

[2] Neuraxis Sleeplab, Buenos Aires, DF, Argentina

[3] Univ Zurich Hosp, Dept Neurol, CH-8091 Zurich, Switzerland

[4] Gui Chauliac Hosp, Dept Neurol, Montpellier, France

来源：

SLEEP MEDICINE | 2006年 / 7卷 / 08期

关键词：

Kleine-Levin syndrome; CSF hypocretin-1; recurrent hypothalamic dysfunction;

D O I：

10.1016/j.sleep.2006.07.003

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

CSF hypocretin-1 measurements were performed during a period of hypersomnia and during an asymptomatic interval in a 14-year-old girl affected with severe Kleine-Levin syndrome. A twofold decrease in hypocretin-1 was evidenced during the period of hypersomnia in comparison with the asymptomatic interval. Together with previous data, this result is in favour of recurrent dysfunction at the hypothalamic level in Kleine-Levin syndrome. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：649 / 651

页数：3

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