Force and voltage sensors in one structure

被引:17
作者
Bezanilla, F [1 ]
Perozo, E
机构
[1] Univ Calif Los Angeles, Dept Physiol & Anesthesiol, Los Angeles, CA 90095 USA
[2] Univ Virginia, Sch Med, Dept Mol Physiol & Biol Phys, Charlottesville, VA 22908 USA
关键词
D O I
10.1126/science.1079369
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:1562 / 1563
页数:2
相关论文
共 15 条
  • [1] Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel
    Bass, RB
    Strop, P
    Barclay, M
    Rees, DC
    [J]. SCIENCE, 2002, 298 (5598) : 1582 - 1587
  • [2] The voltage sensor in voltage-dependent ion channels
    Bezanilla, F
    [J]. PHYSIOLOGICAL REVIEWS, 2000, 80 (02) : 555 - 592
  • [3] Blount P, 1999, Methods Enzymol, V294, P458
  • [4] Structure of the MscL homolog from Mycobacterium tuberculosis:: A gated mechanosensitive ion channel
    Chang, G
    Spencer, RH
    Lee, AT
    Barclay, MT
    Rees, DC
    [J]. SCIENCE, 1998, 282 (5397) : 2220 - 2226
  • [5] CUI C, 1995, J MEMBRANE BIOL, V144, P31
  • [6] The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity
    Doyle, DA
    Cabral, JM
    Pfuetzner, RA
    Kuo, AL
    Gulbis, JM
    Cohen, SL
    Chait, BT
    MacKinnon, R
    [J]. SCIENCE, 1998, 280 (5360) : 69 - 77
  • [7] The open pore conformation of potassium channels
    Jiang, YX
    Lee, A
    Chen, JY
    Cadene, M
    Chait, BT
    MacKinnon, R
    [J]. NATURE, 2002, 417 (6888) : 523 - 526
  • [8] Protection of Escherichia coli cells against extreme turgor by activation of MscS and MscL mechanosensitive channels:: identification of genes required for MscS activity
    Levina, N
    Tötemeyer, S
    Stokes, NR
    Louis, P
    Jones, MA
    Booth, IR
    [J]. EMBO JOURNAL, 1999, 18 (07) : 1730 - 1737
  • [9] PRESSURE-SENSITIVE ION CHANNEL IN ESCHERICHIA-COLI
    MARTINAC, B
    BUECHNER, M
    DELCOUR, AH
    ADLER, J
    KUNG, C
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (08) : 2297 - 2301
  • [10] Open channel structure of MscL and the gating mechanism of mechanosensitive channels
    Perozo, E
    Cortes, DM
    Sompornpisut, P
    Kloda, A
    Martinac, B
    [J]. NATURE, 2002, 418 (6901) : 942 - 948