On the polymorphism of aspirin

被引:131
作者
Bond, Andrew D.
Boese, Roland
Desiraju, Gautam R.
机构
[1] Univ Duisburg Essen, Inst Anorgan Chem, D-45117 Essen, Germany
[2] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India
[3] Unic So Denmark, Dept Chem & Phys, DK-5230 Odense, Denmark
关键词
aspirin; polymorphism; structure determination; X-ray diffraction;
D O I
10.1002/anie.200602378
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) More headaches with aspirin: No new polymorph? Reduction and re-indexing of X-ray data collected on a crystal of the well-known form I of aspirin in a unit cell recently reported for the new form 11 results in a data set from which this so-called new form can be obtained and even refined isotropically! Form II, if it exists, needs to be identified with more rigorous experimentation and modeling. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:615 / 617
页数:3
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