Drug-induced linear immunoglobulin A bullous disease that clinically mimics toxic epidermal necrolysis

被引:20
作者
Mofid, MZ
Costarangos, C
Bernstein, B
Wong, L
Munster, A
Nousari, HC
机构
[1] Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
[2] Johns Hopkins Med Inst, Div Plast & Reconstruct Surg, Baltimore, MD 21205 USA
[3] Johns Hopkins Bayview Med Ctr, Baltimore Reg Burn Ctr, Baltimore, MD USA
来源
JOURNAL OF BURN CARE & REHABILITATION | 2000年 / 21卷 / 03期
关键词
D O I
10.1097/00004630-200021030-00010
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Drug-induced linear immunoglobulin A bullous disease is a subepidermal blistering disorder that most commonly occurs after exposure to vancomycin. It can clinically mimic toxic epidermolyic necrolysis. We describe an 87-year-old white woman in whom linear immunoglobulin A bullous disease developed while she was taking vancomycin and phenytoin. A few days after the linear immunoglobulin A bullous disease developed, both medications were discontinued. No new bullae developed, and the eruption completely resolved within 2 weeks. The patient was treated with only topical therapy.
引用
收藏
页码:246 / 247
页数:2
相关论文
共 4 条
[1]  
COLLINS BA, 1997, MANUAL CLIN LAB IMMU, P422
[2]   IMMUNO-DERMATOLOGY UPDATE - THE IMMUNOLOGICALLY MEDIATED VESICULOBULLOUS DISEASES [J].
HELM, KF ;
PETERS, MS .
MAYO CLINIC PROCEEDINGS, 1991, 66 (02) :187-202
[3]   DRUG-INDUCED LINEAR IGA BULLOUS DERMATOSIS - REPORT OF 6 CASES AND REVIEW OF THE LITERATURE [J].
KUECHLE, MK ;
STEGEMEIR, E ;
MAYNARD, B ;
GIBSON, LE ;
LEIFERMAN, KM ;
PETERS, MS .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1994, 30 (02) :187-192
[4]   Clinical, demographic, and immunohistologic features of vancomycin-induced linear IgA bullous disease of the skin - Report of 2 cases and review of the literature [J].
Nousari, HC ;
Kimyai-Asadi, A ;
Caeiro, JP ;
Anhalt, GJ .
MEDICINE, 1999, 78 (01) :1-8