Drug-induced linear immunoglobulin A bullous disease that clinically mimics toxic epidermal necrolysis
被引:20
作者:
Mofid, MZ
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Mofid, MZ
Costarangos, C
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Costarangos, C
Bernstein, B
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Bernstein, B
Wong, L
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Wong, L
Munster, A
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Munster, A
Nousari, HC
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机构:Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
Nousari, HC
机构:
[1] Johns Hopkins Med Inst, Dept Dermatol, Div Dermatoimmunol, Baltimore, MD 21205 USA
[2] Johns Hopkins Med Inst, Div Plast & Reconstruct Surg, Baltimore, MD 21205 USA
[3] Johns Hopkins Bayview Med Ctr, Baltimore Reg Burn Ctr, Baltimore, MD USA
来源:
JOURNAL OF BURN CARE & REHABILITATION
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2000年
/
21卷
/
03期
关键词:
D O I:
10.1097/00004630-200021030-00010
中图分类号:
R4 [临床医学];
学科分类号:
1002 ;
100602 ;
摘要:
Drug-induced linear immunoglobulin A bullous disease is a subepidermal blistering disorder that most commonly occurs after exposure to vancomycin. It can clinically mimic toxic epidermolyic necrolysis. We describe an 87-year-old white woman in whom linear immunoglobulin A bullous disease developed while she was taking vancomycin and phenytoin. A few days after the linear immunoglobulin A bullous disease developed, both medications were discontinued. No new bullae developed, and the eruption completely resolved within 2 weeks. The patient was treated with only topical therapy.