Carbon Dots as Nontoxic and High-Performance Fluorescence Imaging Agents

被引：789

作者：

Yang, Sheng-Tao ^{[1
,2
,3
]}

Wang, Xin ^{[2
,3
]}

Wang, Haifang ^{[1
,4
]}

Lu, Fushen ^{[2
,3
]}

Luo, Pengju G. ^{[2
,3
]}

Cao, Li ^{[2
,3
]}

Meziani, Mohammed J. ^{[2
,3
]}

Liu, Jia-Hui ^{[1
]}

Liu, Yuanfang ^{[1
,4
]}

Chen, Min ^{[5
]}

Huang, Yipu ^{[5
]}

Sun, Ya-Ping ^{[2
,3
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Beijing Natl Lab Mol Sci, Beijing 100871, Peoples R China

[2] Clemson Univ, Dept Chem, Clemson, SC 29634 USA

[3] Clemson Univ, Lab Emerging Mat & Technol, Clemson, SC 29634 USA

[4] Shanghai Univ, Inst Nanochem & Nanobiol, Shanghai 200444, Peoples R China

[5] Xiamen Univ, Lab Mass Spectrometry, Dept Oceanog, Xiamen 361005, Peoples R China

来源：

JOURNAL OF PHYSICAL CHEMISTRY C | 2009年 / 113卷 / 42期

关键词：

QUANTUM DOTS; NANOPARTICLES; CYTOTOXICITY; NANOTUBES; BIODISTRIBUTION; NANOCRYSTALS; TOXICOLOGY; CLEARANCE; TOXICITY; PARTICLE;

D O I：

10.1021/jp9085969

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Fluorescent carbon dots (small carbon nanoparticles with the surface passivated by oligomeric PEG molecules) were evaluated for their cytotoxicity and in vivo toxicity and also for their optical imaging performance in reference to that of the commercially supplied CdSe/ZnS quantum dots. The results suggested that the carbon dots were biocompatible, and their performance as fluorescence imaging agents was competitive. The implication to the use of carbon dots for in vitro and in vivo applications is discussed.

引用

页码：18110 / 18114

页数：5

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