A study of the effectiveness of high-frequency left prefrontal cortex transcranial magnetic stimulation in major depression in patients who have not responded to right-sided stimulation

被引：30

作者：

Fitzgerald, Paul B. ^{[1
]}

McQueen, Susan ^{[1
]}

Herring, Sally ^{[1
]}

Hoy, Kate ^{[1
]}

Segrave, Rebecca ^{[1
]}

Kulkarni, Jayashri ^{[1
]}

Daskalakis, Zafiris J. ^{[2
]}

机构：

[1] Alfred & Monash Univ, Dept Psychol Med, Alfred Psychiat Res Ctr, Melbourne, Vic 3004, Australia

[2] Ctr Addict & Mental Hlth, Toronto, ON, Canada

来源：

PSYCHIATRY RESEARCH | 2009年 / 169卷 / 01期

基金：

澳大利亚国家健康与医学研究理事会; 英国医学研究理事会;

关键词：

Repetitive transcranial magnetic stimulation; Depression; Prefrontal cortex; Response; Remission; Antidepressant; DOUBLE-BLIND; CONTROLLED-TRIAL; SLOW; RTMS; EFFICACY; SCALE; TMS;

D O I：

10.1016/j.psychres.2008.06.017

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

The objective of this study was to explore the response rate to high-frequency left-sided repetitive transcranial magnetic stimulation (rTMS) in patients who had failed to respond to right-sided low-frequency stimulation, and to investigate whether there was differential efficacy between stimulation at 5 or 10 Hz. Data from two randomized controlled trials were pooled. In both studies a group of patients were randomized to receive either 5- or 10-Hz left prefrontal rTMS after failing to respond to right-sided stimulation. These patients received blinded 5- or 10-Hz stimulation (but without a sham control) for a period of up to 4 weeks and outcomes were compared. There was a small but significant overall response to left-sided rTMS but no difference in response between the 5- and 10-Hz treatment conditions. There appears to be a significant but modest likelihood of response to left-sided TMS in patients who fail right-sided stimulation, but there is no difference in efficacy between 5- and 10-Hz stimulation. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：12 / 15

页数：4

共 26 条

[1] A controlled study of repetitive transcranial magnetic stimulation in medication-resistant major depression [J].

Avery, DH ;

Holtzheimer, PE ;

Fawaz, W ;

Russo, J ;

Neumaier, J ;

Dunner, DL ;

Haynor, DR ;

Claypoole, KH ;

Wajdik, C ;

Roy-Byrne, P .

BIOLOGICAL PSYCHIATRY, 2006, 59 (02) :187-194

[2]

Beck A., 1996, MANUAL BECK DEPRESSI

[3] A randomized clinical trial of repetitive transcranial magnetic stimulation in the treatment of major depression [J].

Berman, RM ;

Narasimhan, M ;

Sanacora, G ;

Miano, AP ;

Hoffman, RE ;

Hu, XS ;

Charney, DS ;

Boutros, NN .

BIOLOGICAL PSYCHIATRY, 2000, 47 (04) :332-337

[4] Antidepressant effects of different schedules of repetitive transcranial magnetic stimulation vs. clomipramine in patients with major depression: relationship to changes in cortical excitability [J].

Chistyakov, AV ;

Kaplan, B ;

Rubichek, O ;

Kreinin, I ;

Koren, D ;

Feinsod, M ;

Klein, E .

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2005, 8 (02) :223-233

[5] Priming stimulation enhances the effectiveness of low-frequency right prefrontal cortex transcranial magnetic stimulation in major depression [J].

Fitzgerald, Paul B. ;

Hoy, Kate ;

McQueen, Susan ;

Herring, Sally ;

Segrave, Rebecca ;

Been, Greg ;

Kulkarni, Jayashri ;

Daskalakis, Zafiris J. .

JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2008, 28 (01) :52-58

[6] A Review of Developments in Brain Stimulation and the Treatment of Psychiatric Disorders [J].

Fitzgerald, Paul B. .

CURRENT PSYCHIATRY REVIEWS, 2006, 2 (02) :199-205

[7] A randomized trial of low-frequency right-prefrontal-cortex transcranial magnetic stimulation as augmentation in treatment-resistant major depression [J].

Fitzgerald, Paul B. ;

Huntsman, Stephen ;

Gunewardene, Ranil ;

Kulkarni, Jayashri ;

Daskalakis, Z. Jeff .

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 (06) :655-666

[8] Transcranial magnetic stimulation in the treatment of depression - A double-blind, placebo-controlled trial [J].

Fitzgerald, PB ;

Brown, TL ;

Marston, NAU ;

Daskalakis, ZJ ;

de Castella, A ;

Kulkarni, J .

ARCHIVES OF GENERAL PSYCHIATRY, 2003, 60 (10) :1002-1008

[9] A randomized, controlled trial of sequential bilateral repetitive transcranial magnetic stimulation for treatment-resistant depression [J].

Fitzgerald, PB ;

Benitez, J ;

de Castella, A ;

Daskalakis, ZJ ;

Brown, TL ;

Kulkarni, J .

AMERICAN JOURNAL OF PSYCHIATRY, 2006, 163 (01) :88-94

[10] A controlled trial of daily left prefrontal cortex TMS for treating depression [J].

George, MS ;

Nahas, Z ;

Molloy, M ;

Speer, AM ;

Oliver, NC ;

Li, XB ;

Arana, GW ;

Risch, SC ;

Ballenger, JC .

BIOLOGICAL PSYCHIATRY, 2000, 48 (10) :962-970

← 1 2 3 →