A survey of the prophylaxis and treatment of acute GVHD in Europe: A report of the European Group for Blood and Marrow Transplantation (EBMT)

被引:103
作者
Ruutu, T
Niederwieser, D
Gratwohl, A
Apperley, JF
机构
[1] UNIV INNSBRUCK, DEPT INTERNAL MED, DIV CLIN IMMUNOL, A-6020 INNSBRUCK, AUSTRIA
[2] KANTONSSPITAL, DEPT INTERNAL MED & RES, DIV HAEMATOL, CH-4031 BASEL, SWITZERLAND
[3] ROYAL POSTGRAD MED SCH, DEPT HAEMATOL, LONDON W12 0HS, ENGLAND
关键词
acute graft-versus-host disease; prophylaxis; treatment; cyclosporine A; methotrexate; corticosteroids;
D O I
10.1038/sj.bmt.1700745
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A survey was carried out among EBMT (European Group for Blood and Marrow Transplantation) centres of the practical details of the prophylaxis and treatment of acute GVHD. The emphasis was on the prophylactic use of cyclosporine A and methotrexate and their combination, and on the initial treatment of acute GVHD. Eighty-seven centres sent a report. This survey demonstrated that marked differences exist between centres in the practices of GVHD prophylaxis and treatment despite superficially similar protocols, These differences may have an impact on the results obtained.
引用
收藏
页码:759 / 764
页数:6
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