Drivers of biodiagnostic development

被引：693

作者：

Giljohann, David A. ^{[1
,2
]}

Mirkin, Chad A. ^{[1
,2
]}

机构：

[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[2] Northwestern Univ, Int Inst Nanotechnol, Evanston, IL 60208 USA

来源：

NATURE | 2009年 / 462卷 / 7272期

基金：

美国国家卫生研究院; 美国国家科学基金会;

关键词：

ULTRASENSITIVE DETECTION; COLORIMETRIC DETECTION; DNA; NANOPARTICLES; IMMUNOASSAY; MOLECULES; PROTEINS;

D O I：

10.1038/nature08605

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];

摘要：

The promise of point-of-care medical diagnostics - tests that can be carried out at the site of patient care is enormous, bringing the benefits of fast and reliable testing and allowing rapid decisions on the course of treatment to be made. To this end, much innovation is occurring in technologies for use in biodiagnostic tests. Assays based on nanomaterials, for example, are now beginning to make the transition from the laboratory to the clinic. But the potential for such assays to become part of routine medical testing depends on many scientific factors, including sensitivity, selectivity and versatility, as well as technological, financial and policy factors.

引用

页码：461 / 464

页数：4

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