Ecalectin/galectin-9, a novel eosinophil chemoattractant: Its function and production

被引：47

作者：

Hirashima, M ^{[1
]}

机构：

[1] Kagawa Med Sch, Dept Immunol & Immunopathol, Kagawa 76107, Japan

来源：

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY | 2000年 / 122卷

关键词：

ecalectin; galectin; eosinophil; chemoattraction; regulation;

D O I：

10.1159/000053623

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

We have recently succeeded in purifying and cloning a novel eosinophil chemoattractant, ecalectin/galectin-9, which belong to a rapidly growing galectin family. The eosinophil chemoattractant activity of ecalectin is potent and selective for eosinophils. The cellular source of ecalectin has been thought to be antigen-stimulated T cells. Herein, we will review the significance of its divalent galactoside-binding activity in ecalectin-induced eosinophil chemoattraction and the regulation of ecalectin expression in immune cells. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：6 / 9

页数：4

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