Neopentyl ester protecting groups for arylsulfonic acids

被引：46

作者：

Roberts, JC ^{[1
]}

Gao, H ^{[1
]}

Gopalsamy, A ^{[1
]}

Kongsjahju, A ^{[1
]}

Patch, RJ ^{[1
]}

机构：

[1] PROCEPT INC,DEPT RAT DRUG DESIGN,CAMBRIDGE,MA 02139

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 03期

关键词：

D O I：

10.1016/S0040-4039(96)02302-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We report that neopentylsulfonate esters are stable to a variety of standard organic reaction conditions and are easily cleaved to sulfonic acids. We also discuss the use of N-Boc4-amino-2,2-dimethylbutyl-1-sulfonate esters which may be cleaved under conditions that are suitable far solid phase synthesis. Copyright (C) 1996 Elsevier Science Ltd

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页码：355 / 358

页数：4

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