Postoperative stroke in a child with cerebral palsy heterozygous for factor V Leiden

被引：19

作者：

Steiner, M

Hodes, MZ

Shreve, M

Sundberg, S

Edson, JR

机构：

[1] Univ Minnesota, Fairview Univ Med Ctr, Dept Pediat, Div Hematol, Minneapolis, MN 55455 USA

[2] Univ Minnesota, Fairview Univ Med Ctr, Dept Pediat, Div Oncol, Minneapolis, MN 55455 USA

[3] Univ Minnesota, Fairview Univ Med Ctr, Dept Pediat, Div Blood & Marrow Transplant, Minneapolis, MN 55455 USA

[4] Univ Minnesota, Fairview Univ Med Ctr, Dept Pediat, Div Pulm Crit Care, Minneapolis, MN 55455 USA

[5] Univ Minnesota, Fairview Univ Med Ctr, Dept Lab Med & Pathol, Minneapolis, MN 55455 USA

[6] Albany Med Coll, Dept Med, Albany, NY 12208 USA

[7] Albany Med Coll, Dept Pediat, Albany, NY 12208 USA

[8] Gillette Childrens Hosp, Dept Orthoped Surg, St Paul, MN USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2000年 / 22卷 / 03期

关键词：

factor V Leiden; childhood ischemic stroke; postoperative complications; cerebral palsy; special-needs children;

D O I：

10.1097/00043426-200005000-00014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 5-year-old with spastic quadraparetic cerebral palsy suffered multiple strokes after extensive orthopedic surgery. Coagulation testing was undertaken to determine whether a familial thrombophilia was present. The patient was found to be heterozygous for factor V Leiden. Factor V Leiden may be a risk factor for central nervous system events in special-needs children, particularly when common medical conditions create additional procoagulant risks.

引用

页码：262 / 264

页数：3

共 11 条

[1]

Aschka I, 1996, EUR J PEDIATR, V155, P1009

[2] MUTATION IN BLOOD-COAGULATION FACTOR-V ASSOCIATED WITH RESISTANCE TO ACTIVATED PROTEIN-C [J].