Sequential 1,3-dipolar cycloaddition-Pictet-Spengler reactions. A versatile tactical combination

被引：32

作者：

Dondas, HA

Duraisingham, J

Grigg, R ^{[1
]}

MacLachlan, WS

MacPherson, DT

Thornton-Pett, M

Sridharan, V

Suganthan, S

机构：

[1] Univ Leeds, Sch Chem, MIDAS, Leeds LS2 9JT, W Yorkshire, England

[2] SmithKline Beecham, Harlow CM19 5AW, Essex, England

来源：

TETRAHEDRON | 2000年 / 56卷 / 24期

关键词：

metallo-azomethine ylides; Ag catalysis; cycloaddition; Pictet-Spengler reactions;

D O I：

10.1016/S0040-4020(00)00320-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The combination of thermal or Ag(I) catalysed imine-->azomethine ylide-->cycloaddition cascades with a subsequent Pictet-Spengler reaction allows the assembly of polyfunctional N-heterocycles, via formation of 4 bonds and 2 rings, in good yield. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：4063 / 4070

页数：8

共 13 条

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