Dynamic left ventricular dyssynchrony: a potential cause of no contractile reserve in patients with low-gradient aortic stenosis

被引：6

作者：

Lancellotti, Patrizio ^{[1
]}

Szymanski, Catherine ^{[2
]}

Moonen, Marie ^{[1
]}

Garweg, Christophe ^{[1
]}

O'Connor, Kim ^{[1
]}

Tribouilloy, Christophe ^{[2
]}

Pierard, Luc A. ^{[1
]}

机构：

[1] Univ Hosp Liege, Dept Cardiol, B-4000 Liege, Belgium

[2] Univ Hosp Amiens, Dept Cardiol, Picardie, France

来源：

EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY | 2009年 / 10卷 / 07期

关键词：

Aortic stenosis; Low gradient; Left ventricular dyssynchrony; VALVE-REPLACEMENT; RISK STRATIFICATION; STRESS; MULTICENTER; PROGNOSIS;

D O I：

10.1093/ejechocard/jep079

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Dobutamine stress echocardiography (DSE) has the potential to stratify patients with low-gradient aortic stenosis (AS) but Little is known about ventricular dyssynchrony associated with AS. We report the case of a patient who presented AS associated with left ventricular (LV) dyssynchrony. A DSE was performed, which showed no contractile reserve but an increase in LV dyssynchrony. In this patient, the reduced aortic valve area was probably because of the association of inadequate forward stroke volume due to ischaemic cardiomyopathy and fixed severe AS. The cause of LV dysfunction may include a certain degree of intrinsic myocardial dysfunction due to ischaemic cardiomyopathy and afterload mismatch associated with dynamic LV dyssynchrony, which could be a determinant of forward stroke volume response.

引用

页码：880 / 883

页数：4

共 17 条

[1]

The potential of myocardial perfusion scintigraphy for risk stratification of asymptomatic patients with type 2 diabetes [J].

Bax, Jeroen J. ;

Bonow, Robert O. ;

Tschoepe, Diethelm ;

Inzucchi, Silvio E. ;

Barrett, Eugene .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 48 (04) :754-760

[2]

B-Type natriuretic peptide in low-flow, low-gradient aortic stenosis - Relationship to hemodynamics and clinical outcome: Results from the multicenter truly or pseudo-severe aortic stenosis (TOPAS) study [J].

Bergler-Klein, Jutta ;

Mundigler, Gerald ;

Pibarot, Philippe ;

Burwash, Ian G. ;

Dumesnil, Jean G. ;

Blais, Claudia ;

Fuchs, Christina ;

Mohty, Dania ;

Beanlands, Rob S. ;

Hachicha, Zeineb ;

Walter-Publig, Nicole ;

Rader, Florian ;

Baumgartner, Helmut .

CIRCULATION, 2007, 115 (22) :2848-2855

[3]

PROGNOSIS AFTER VALVE-REPLACEMENT IN PATIENTS WITH SEVERE AORTIC-STENOSIS AND A LOW TRANSVALVULAR PRESSURE-GRADIENT [J].

BROGAN, WC ;

GRAYBURN, PA ;

LANGE, RA ;

HILLS, LD .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1993, 21 (07) :1657-1660

[4]

HEMODYNAMIC DETERMINANTS OF PROGNOSIS OF AORTIC-VALVE REPLACEMENT IN CRITICAL AORTIC-STENOSIS AND ADVANCED CONGESTIVE HEART-FAILURE [J].

CARABELLO, BA ;

GREEN, LH ;

GROSSMAN, W ;

COHN, LH ;

KOSTER, JK ;

COLLINS, JJ .

CIRCULATION, 1980, 62 (01) :42-48

[5]

The effect of pharmacological stress on intraventricular dyssynchrony in left ventricular systolic dysfunction [J].

Chattopadhyay, Sudipta ;

Alamgir, Mohammed F. ;

Nikitin, Nikolay P. ;

Fraser, Alan G. ;

Clark, Andrew L. ;

Cleland, John G. F. .

EUROPEAN JOURNAL OF HEART FAILURE, 2008, 10 (04) :412-420

[6]

Dynamic ventricular dyssynchrony - An exercise-echocardiography study [J].

Lafitte, Stephane ;

Bordachar, Pierre ;

Lafitte, Marianne ;

Garrigue, Stephane ;

Reuter, Sylvain ;

Reant, Patricia ;

Serri, Karim ;

Lebouffos, Valerie ;

Berrhouet, Marianne ;

Jais, Pierre ;

Haissaguerre, Michel ;

Clementy, Jacques ;

Roudaut, Raymond ;

DeMaria, Anthony N. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2006, 47 (11) :2253-2259

[7]

Effect of dynamic left ventricular dyssynchrony on dynamic mitral regurgitation in patients with heart failure due to coronary artery disease [J].

Lancellotti, P ;

Stainier, PY ;

Lebois, F ;

Piérard, LA .

AMERICAN JOURNAL OF CARDIOLOGY, 2005, 96 (09) :1304-1307

[8]

Low-gradient aortic stenosis: impact of prosthesis-patient mismatch on survival [J].

Monin, Jean-Luc ;

Monchi, Mehran ;

Kirsch, Matthias E. W. ;

Petit-Eisenmann, Helene ;

Baleynaud, Serge ;

Chauvel, Christophe ;

Metz, Damien ;

Adams, Catherine ;

Quere, Jean-Paul ;

Gueret, Pascal ;

Tribouilloy, Christophe .

EUROPEAN HEART JOURNAL, 2007, 28 (21) :2620-2626

[9]

Low-gradient aortic stenosis -: Operative risk stratification and predictors for long-term outcome:: A multicenter study using dobutamine stress hemodynamics [J].

Monin, JL ;

Quéré, JP ;

Monchi, M ;

Petit, H ;

Baleynaud, S ;

Chauvel, C ;

Pop, C ;

Ohlmann, P ;

Lelguen, C ;

Dehant, P ;

Tribouilloy, C ;

Guéret, P .

CIRCULATION, 2003, 108 (03) :319-324

[10]

Aortic stenosis with severe left ventricular dysfunction and low transvalvular pressure gradients - Risk stratification by low-dose dobutamine echocardiography [J].

Monin, JL ;

Monchi, M ;

Gest, V ;

Duval-Moulin, AM ;

Dubois-Rande, JL ;

Gueret, P .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2001, 37 (08) :2101-2107

← 1 2 →