Prevalence and incidence of gallstones in liver cirrhosis

被引:43
作者
delOlmo, JA
Garcia, F
Serra, MA
Maldonado, L
Rodrigo, JM
机构
[1] UNIV VALENCIA,HOSP CLIN,SERV HEPATOL,VALENCIA,SPAIN
[2] UNIV VALENCIA,HOSP CLIN,SERV DIAGNOST RADIOL,VALENCIA,SPAIN
关键词
cholelithiasis; hepatobiliary ultrasonography; liver cirrhosis;
D O I
10.3109/00365529709011225
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background: Our aim was to assess the prevalence and incidence of gallstone disease in patients with liver cirrhosis and to identify risk factors for cholecystolithiasis. Methods: We studied a cohort of 313 patients with liver cirrhosis confirmed by histology and/or laparoscopy and 357 patients free of liver disease, who had been referred for ultrasonographic examination of the upper abdomen. Hepatobiliary ultrasonography was performed when liver cirrhosis was diagnosed and every 6 months thereafter. Risk factors for cholelithiasis (age, gender, diet, pregnancy, diabetes, family history of cholelithiasis, etiology of cirrhosis, decompensated disease) were assessed. Results: The overall prevalence of gallstones in cirrhotic patients was 23.3%. In controls, the overall prevalence of cholecystolithiasis was 16.8%. After a median follow-up period of 65 months, 30 patients developed gallstones. The calculated annual incidence was 3.4%. Conclusions: Given that the prevalence of gallstone disease is higher in cirrhotics than in noncirrhotic patients, cirrhosis of the liver may be considered a risk factor for cholecystolithiasis.
引用
收藏
页码:1061 / 1065
页数:5
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