Exploring cocrystal -: cocrystal reactivity via liquid-assisted grinding:: the assembling of racemic and dismantling of enantiomeric cocrystals

被引：107

作者：

Friscic, Tomislav

Fabian, Laszlo

Burley, Jonathan C.

Jones, William

Motherwell, W. D. Samuel

机构：

[1] Univ Cambridge, Dept Chem, Pfizer Inst Pharmaceut Mat Sci, Cambridge CB2 1EW, England

[2] Cambridge Crystallog Data Ctr, Cambridge CB2 1EZ, England

[3] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 48期

关键词：

D O I：

10.1039/b613073a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.

引用

页码：5009 / 5011

页数：3

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