Simplified laser fluorescence scanner for proteomics studies and early cancer diagnosis

被引:15
作者
Kim, BC [1 ]
Jeong, JH [1 ]
Jeong, DS [1 ]
Choi, EY [1 ]
Kim, JH [1 ]
Nahm, KB [1 ]
机构
[1] Biomed Photon Inc, Chunchon, Kangwon, South Korea
来源
OPTICS IN HEALTH CARE AND BIOMEDICAL OPTICS: DIAGNOSTICS AND TREATMENT | 2002年 / 4916卷
关键词
fluorescence; scanner; cancer diagnosis; cancer specific agent; ID scanner;
D O I
10.1117/12.482938
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A compact integral system was developed capable of quantitatively measuring analytes in biological fluids. This system uses the fluorescence as a reporter molecule to provide the information about the molecular density of the target molecule in the test sample. Developed for the purpose of providing an affordable means of fast point-of-care testing of marker molecules specifically arranged in the specimen, this system proved to be able to detect the presence of the marker agent at the level of 50 pg/ml in less than 15 minutes, with the actual measurement taking less than 1.5 minutes. The design concept for this unit is presented together with the result for a few representative samples.
引用
收藏
页码:103 / 108
页数:6
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