Molecular mechanisms of pancreatic cancer and potential targets of treatment

被引:10
作者
Aho, Ursula
Zhao, Xia
Loehr, Matthias
Andersson, Roland [1 ]
机构
[1] Lund Univ, Dept Surg, Univ Lund Hosp, SE-22185 Lund, Sweden
[2] Univ Heidelberg, Med Fac Mannheim, Dept Med 2, Heidelberg, Germany
关键词
D O I
10.1080/00365520601106384
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
[No abstract available]
引用
收藏
页码:279 / 296
页数:18
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共 209 条
[1]   Preclinical and clinical evaluation of proteasome inhibitor PS-341 for the treatment of cancer [J].
Adams, J .
CURRENT OPINION IN CHEMICAL BIOLOGY, 2002, 6 (04) :493-500
[2]   Cyclooxygenase-2 expression associated with severity of PanIN lesions: A possible link between chronic pancreatitis and pancreatic cancer [J].
Albazaz, R ;
Verbeke, CS ;
Rahman, SH ;
McMahon, MJ .
PANCREATOLOGY, 2005, 5 (4-5) :361-369
[3]   PS-341 and gemcitabine in patients with metastatic pancreatic adenocarcinoma: a North Central Cancer Treatment Group (NCCTG) randomized phase II study [J].
Alberts, SR ;
Foster, NR ;
Morton, RF ;
Kugler, J ;
Schaefer, P ;
Wiesenfeld, M ;
Fitch, TR ;
Steen, P ;
Kim, GP ;
Gill, S .
ANNALS OF ONCOLOGY, 2005, 16 (10) :1654-1661
[4]   Mechanism of activation and function of protein kinase B [J].
Alessi, DR ;
Cohen, P .
CURRENT OPINION IN GENETICS & DEVELOPMENT, 1998, 8 (01) :55-62
[5]   Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy [J].
Ali, S ;
El-Rayes, BF ;
Sarkar, FH ;
Philip, PA .
MOLECULAR CANCER THERAPEUTICS, 2005, 4 (12) :1943-1951
[6]   MOST HUMAN CARCINOMAS OF THE EXOCRINE PANCREAS CONTAIN MUTANT C-K-RAS GENES [J].
ALMOGUERA, C ;
SHIBATA, D ;
FORRESTER, K ;
MARTIN, J ;
ARNHEIM, N ;
PERUCHO, M .
CELL, 1988, 53 (04) :549-554
[7]  
ANDERSSON R, 2001, ANN GASTROENTEROL, V13, P221
[8]  
ANDRENSANDBERG A, 2005, PANCREATIC TUMORS ST
[9]  
[Anonymous], ASCO M
[10]   Overexpression of TGF-β by infiltrated granulocytes correlates with the expression of collagen mRNA in pancreatic cancer [J].
Aoyagi, Y ;
Oda, T ;
Kinoshita, T ;
Nakahashi, C ;
Hasebe, T ;
Ohkohchi, N ;
Ochiai, A .
BRITISH JOURNAL OF CANCER, 2004, 91 (07) :1316-1326