Erythromycin-resistant pharyngeal isolates of Streptococcus pyogenes recovered in Italy

被引：33

作者：

Dicuonzo, G

Fiscarelli, E

Gherardi, G

Lorino, G

Battistoni, F

Landi, S

De Cesaris, M

Petitti, T

Beall, B ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, WHO Collaborating Ctr Stroptococcal Res, Resp Dis Branch, Atlanta, GA 30333 USA

[2] Univ Roma La Sapienza, Ist Microbiol, Rome, Italy

[3] Bambino Gesu Pediat Hosp, Dept Lab Med, Rome, Italy

[4] Bambino Gesu Pediat Hosp, Hosp Infect Control Program, Rome, Italy

[5] Bambino Gesu Pediat Hosp, Univ Campus Biomed, Rome, Italy

[6] Bambino Gesu Pediat Hosp, Serv Med Lab, Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2002年 / 46卷 / 12期

关键词：

D O I：

10.1128/AAC.46.12.3987-3990.2002

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Three classes of macrolide resistance phenotypes and three different erythromycin resistance determinants were found among 127 erythromycin-resistant group A streptococcal (GAS) isolates recovered from 355 (35.8%) pediatric pharyugitis patients in Rome, Italy. According to emm and sof sequence typing results, erythromycin-resistant isolates comprised 11 different clonal types. Remarkably, 126 of the 127 macrolide-resistant isolates were serum opacity factor (sof) gene positive. These data suggest a strong association between macrolide resistance and the presence of sof among GAS isolates recovered from Italian pediatric pharyngitis patients.

引用

页码：3987 / 3990

页数：4

共 42 条

[1]

[Anonymous], 2000, M2A7 NCCLS

[2] Streptococcus pyogenes collected in Torino (northwest Italy) between 1983 and 1998:: Survey of macrolide resistance and trend of genotype by RAPD [J].