Physiology of Hemostasis: With Relevance to Current and Future Laboratory Testing

被引：4

作者：

Kriz, Nancy ^{[3
]}

Rinder, Christine S. ^{[1
]}

Rinder, Henry M. ^{[2
]}

机构：

[1] Yale Univ, Sch Med, Dept Anesthesiol, Yale New Haven Hosp, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Dept Internal Med Hematol, Yale New Haven Hosp, New Haven, CT 06520 USA

[3] Yale Univ, Sch Med, Dept Lab Med, Yale New Haven Hosp,Coagulat Lab, New Haven, CT 06520 USA

来源：

CLINICS IN LABORATORY MEDICINE | 2009年 / 29卷 / 02期

关键词：

Hemostasis; Thrombosis; Hemorrhage; Thrombin; Fibrinolysis; Blood platelets; PLASMINOGEN-ACTIVATOR INHIBITOR-1; PLATELET-AGGREGATION; THROMBIN GENERATION; DISORDERS; RISK;

D O I：

10.1016/j.cll.2009.06.004

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

This article briefly details the physiologic and interdependent mechanisms of vascular hemostasis, with an eye toward how the laboratory can assist in diagnosing and maintaining the balance of procoagulant and anticoagulant functions. These functions include determining characteristics of the blood vessel wall, platelet components and receptor-ligand interactions critical for hemostasis, the regulation of thrombin generation and its effects, and the complex fibrinolytic pathways that complete the coagulation cascade.

引用

页码：159 / +

页数：17

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