Differentiation of arterial, venous, and lymphatic endothelial cells from vascular progenitors

被引：37

作者：

Yamashita, Jun K. ^{[1
]}

机构：

[1] Kyoto Univ, Inst Frontier Med Sci, Ctr Stem Cell Res, Lab Stem Cell Differentiat, Kyoto 6068507, Japan

来源：

TRENDS IN CARDIOVASCULAR MEDICINE | 2007年 / 17卷 / 02期

关键词：

D O I：

10.1016/j.tcm.2007.01.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Recent discoveries of molecular markers for arterial, venous, and lymphatic endothelial cells (ECs) made it possible to investigate mechanisms of the vascular diversification at the cellular level. Recently, these three EC types have been successfully induced from mouse embryonic stem cells. Molecular and cellular dissection of EC diversification processes in vitro using embryonic stem cell system would provide novel insights into vascular development and materials for cell therapy as well as gene therapy and novel drugs. Further investigation of tissue-specific vascular diversification in detail would be important for future vascular biology and medicine. (c) 2007, Elsevier Inc.

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页码：59 / 63

页数：5

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