Inflammation, infection, or both in atherosclerosis: The ROXIS trial in perspective

被引：14

作者：

Gurfinkel, E ^{[1
]}

机构：

[1] Favaloro Fdn, Coronary Care Unit, RA-1093 Buenos Aires, DF, Argentina

来源：

JOURNAL OF INFECTIOUS DISEASES | 2000年 / 181卷

关键词：

D O I：

10.1086/315606

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The role of infection in the instability of atherosclerotic plaques has been questioned because of discrepancies in the results of clinical trials that tested antibiotics in acute coronary syndromes. The results of the Randomized Trial of Roxithromycin in Non-Q-Wave Coronary Syndromes (ROXIS) are summarized and contrasted with two other pilot studies of antibiotic therapy of coronary artery disease. Relevant characteristics of patients enrolled and rationales for these trials are discussed and serologic results are presented.

引用

页码：S566 / S568

页数：3

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