Emergence of multidrug-resistant Klebsiella pneumoniae isolates producing VIM-4 metallo-β-lactamase, CTX-M-15 extended-spectrum β-lactamase, and CMY-4 AmpC β-lactamase in a Tunisian university hospital

被引：88

作者：

Ktari, Sonia

Arlet, Guillaume

Mnif, Basma

Gautier, Valerie

Mahjoubi, Fouzia

Ben Jmeaa, Mounir

Bouaziz, Mounir

Hammami, Adnane

机构：

[1] CHU Habib Bourguiba, Microbiol Lab, Sfax, Tunisia

[2] CHU Habib Bourguiba, Serv Malad Infect, Sfax, Tunisia

[3] CHU Habib Bourguiba, Serv Reanimat, Sfax, Tunisia

[4] Univ Paris 06, Fac Med, Bacteriol Lab, UPRES EA 2392, Paris, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 12期

关键词：

D O I：

10.1128/AAC.00663-06

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Klebsiella pneumoniae clinical isolates resistant to carbapenems were recovered from It patients in the hospital of Sfax, Tunisia. The isolates were closely related as shown by pulsed-field gel electrophoresis, and they produced VIM-4 metallo-enzyme, CTX-M-15 extended-spectrum beta-lactamase, and CMY-4 AmpC enzyme. The bla(VIM-4) gene is part of a class 1 integron.

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页码：4198 / 4201

页数：4

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