Immunobiology of dendritic cells

被引：5266

作者：

Banchereau, J ^{[1
]}

Briere, F

Caux, C

Davoust, J

Lebecque, S

Liu, YT

Pulendran, B

Palucka, K

机构：

[1] Baylor Inst Immunol Res, Dallas, TX 75204 USA

[2] Schering Plough Corp, Lab Immunol Res, F-69572 Dardilly, France

[3] DNAX Res Inst Molec & Cellular Biol Inc, Inst Res, Dept Immunobiol, Palo Alto, CA 94304 USA

来源：

ANNUAL REVIEW OF IMMUNOLOGY | 2000年 / 18卷

关键词：

dendritic cell subsets; innate immunity; antigen presentation; chemokines; T cell priming; B cell differentiation;

D O I：

10.1146/annurev.immunol.18.1.767

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Dendritic cells (DCs) are antigen-presenting cells with a unique ability to induce primary immune responses. DCs capture and transfer information from the outside world to the cells of the adaptive immune system. DCs are not only critical for the induction of primary immune responses, but may also be important for the induction of immunological tolerance, as well as for the regulation of the type of T cell-mediated immune response. Although our understanding of DC biology is still in its infancy, we are now beginning to use DC-based immunotherapy protocols to elicit immunity against cancer and infectious diseases.

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页码：767 / +

页数：46

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