Electromagnetic therapeutic angiogenesis: The next step

被引：4

作者：

Cuevas, P ^{[1
]}

Asin-Cardiel, E

机构：

[1] Hosp Ramon & Cajal, Serv Histol, Dept Invest, E-28034 Madrid, Spain

[2] Hosp Ramon & Cajal, Inst Enfermedades Cardiovasc, E-28034 Madrid, Spain

来源：

NEUROLOGICAL RESEARCH | 2000年 / 22卷 / 04期

关键词：

angiogenesis; electrical stimulation; coronary and peripheral artery disease;

D O I：

10.1080/01616412.2000.11740682

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Therapeutic angiogenesis, in the form of growth factor protein administration or gene therapy, is a new method of treatment for patients with severe coronary and peripheral artery disease not amenable to conventional methods of revascularization. Furthermore, a new experimental strategy increases endogenous angiogenesis in ischemic tissue to induce local 'angiogens' by means of electromagnetic stimulation. Further studies examining the molecular basis and clinical efficacy of electromagnetic angiogenesis are necessary.

引用

页码：349 / 350

页数：2

共 19 条

[1]

BARRIOS V, 1995, EUR HEART J SUPPL, V16, P980

[2] Molecular and cellular mechanisms of myocardial stunning [J].

Bolli, R ;

Marbán, E .

PHYSIOLOGICAL REVIEWS, 1999, 79 (02) :609-634

[3] Transmyocardial laser revascularisation compared with continued medical therapy for treatment of refractory angina pectoris: a prospective randomised trial [J].

Burkhoff, D ;

Schmidt, S ;

Schulman, SP ;

Myers, J ;

Resar, J ;

Becker, LC ;

Weiss, J ;

Jones, JW .

LANCET, 1999, 354 (9182) :885-890

[4]

Cuevas P, 1997, Eur J Med Res, V2, P282

[5] SINGLE TOPICAL APPLICATION OF HUMAN RECOMBINANT BASIC FIBROBLAST GROWTH-FACTOR (RBFGF) PROMOTES NEOVASCULARIZATION IN RAT CEREBRAL-CORTEX [J].

CUEVAS, P ;

GIMENEZGALLEGO, G ;

CARCELLER, F ;

CUEVAS, B ;

CRESPO, A .

SURGICAL NEUROLOGY, 1993, 39 (05) :380-384

[6] PROTECTION AGAINST FOCAL CEREBRAL-ISCHEMIA FOLLOWING EXPOSURE TO A PULSED ELECTROMAGNETIC-FIELD [J].

GRANT, G ;

CADOSSI, R ;

STEINBERG, G .

BIOELECTROMAGNETICS, 1994, 15 (03) :205-216

[7]

HARRIS PL, 1995, EUR J VASC ENDOVASC, V10, P108

[8]

Hashimoto Etsuo, 1994, American Journal of Physiology, V267, pH1948

[9] EFFECT OF ELECTRICAL-STIMULATION ON SURVIVAL OF SKIN FLAPS IN PIGS [J].

IM, MJ ;

LEE, WPA ;

HOOPES, JE .

PHYSICAL THERAPY, 1990, 70 (01) :37-40

[10] Establishment of a simple and practical procedure applicable to therapeutic angiogenesis [J].

Kanno, S ;

Oda, N ;

Abe, M ;

Saito, S ;

Hori, K ;

Handa, Y ;

Tabayashi, K ;

Sato, Y .

CIRCULATION, 1999, 99 (20) :2682-2687

← 1 2 →