Regulation of gene expression in industrial fungi:: Trichoderma

被引：139

作者：

Mach, RL ^{[1
]}

Zeilinger, S ^{[1
]}

机构：

[1] Inst Biochem Engn, Microbial Biochem & Gene Technol Grp, A-1060 Vienna, Austria

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2003年 / 60卷 / 05期

关键词：

D O I：

10.1007/s00253-002-1162-x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The genus Trichoderma comprises a group of filamentous ascomycetes that are now widely used in industrial applications because of their ability to produce extracellular hydrolases in large amounts. In addition, strong inducible promoters together with high secretory capacity have made Trichoderma an attractive host for heterologous protein production. Several promoters of genes encoding hydrolytic enzymes have been investigated in detail regarding their cis-acting elements and trans-acting factors. Potent inducer molecules, for both xylanolytic and cellulolytic enzyme systems, have been identified and characterized. Furthermore, models for the recognition of the insoluble substrates cellulose and xylan have been developed based on a large set of experiments. This mini-review summarises the considerable amount of data accumulated over the past three decades.

引用

页码：515 / 522

页数：8

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