MR Imaging Findings in 2 Cases of Late Infantile GM1 Gangliosidosis

被引:30
作者
De Grandis, E. [1 ]
Di Rocco, M. [2 ]
Pessagno, A. [1 ]
Veneselli, E. [1 ]
Rossi, A. [3 ]
机构
[1] Univ Genoa, Gaslini Inst, Div Child Neuropsychiat, Genoa, Italy
[2] Gaslini Inst, Unit Pediat 2, Genoa, Italy
[3] Gaslini Inst, Dept Pediat Neuroradiol, Genoa, Italy
关键词
BRAIN IRON;
D O I
10.3174/ajnr.A1508
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Late infantile GM1 gangliosidosis is a rare lysosomal disorder characterized by mental deterioration and progressive spastic, cerebellar, and extrapyramidal signs, without facial dysmorphisms and organomegaly. Neuroimaging findings have been reported in only a few cases. Here we report on predominant globus pallidus MR signal-intensity abnormalities in 2 patients with the late infantile form of GM1 gangliosidosis.
引用
收藏
页码:1325 / 1327
页数:3
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