Statistics of single-molecule detection

被引：27

作者：

Enderlein, J

Robbins, DL

Ambrose, WP

Goodwin, PM

Keller, RA

机构：

[1] CST-1, MS M888, Los Alamos National Laboratory, Los Alamos

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 1997年 / 101卷 / 18期

关键词：

D O I：

10.1021/jp963261x

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new mathematical approach for the calculation of the photon detection statistics in single-molecule detection experiments is presented. The approach is based on a path integral representation of the involved probability distributions. A numerical Monte Carlo sampling method for computing the involved path integrals is given. The general ideas are applied to the modeling of measured burst size distributions in single-molecule detection experiments with B-phycoerythrin.

引用

收藏

页码：3626 / 3632

页数：7

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