Pollen NAD(P)H oxidases and their contribution to allergic inflammation

被引：11

作者：

Dharajiya, Nilesh G.

Bacsi, Attila

Boldogh, Istvan

Sur, Sanjiv

机构：

[1] Univ Texas, Med Branch,NHLBI,Proteom Ctr, Dept Internal Med, Div Allergy Pulm Immunol Crit Ccare & Sleep, Galveston, TX 77555 USA

[2] Univ Texas, Med Branch, Dept Internal Med, NHLBI Proteom Ctr,Div Sleep, Galveston, TX 77555 USA

[3] Univ Texas, Med Branch, Dept Microbiol & Immunol, Galveston, TX 77555 USA

[4] Univ Debrecen, Inst Immunol, H-4021 Debrecen, Hungary

[5] Univ Texas, Med Branch, Dept Biochem & Mol Biol, NHLBI Proteom Ctr, Galveston, TX 77555 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2007年 / 27卷 / 01期

关键词：

D O I：

10.1016/j.iac.2006.11.007

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

This article provides an overview of NADPH oxidase and its role in allergic inflammation. A background and historical perspectives of NADPH oxidase are first provided, followed by a detailed overview of mammalian NADPH oxidase subunits and their functional organization. Plant NADPH oxidase, the authors' discovery of NADPH oxidase in pollens, and their contribution to allergic inflammation are then discussed, concluding with a discussion of future directions and outstanding questions that require attention.

引用

页码：45 / +

页数：20

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