RNA interference: The fragile X syndrome connection

被引：22

作者：

Carthew, RW ^{[1
]}

机构：

[1] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Evanston, IL 60208 USA

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 24期

关键词：

D O I：

10.1016/S0960-9822(02)01352-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Fragile X syndrome is caused by loss of expression of FMRP, a protein proposed to act as a regulator of mRNA translation which promotes synaptic maturation and function. Now FMRP has been found to associate with the RNP complex that mediates post-transcriptional silencing by RNAi.

引用

页码：R852 / R854

页数：3

共 20 条

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