Prognostic significance of tumour markers in endometrial cancer

被引：39

作者：

Lo, SST ^{[1
]}

Cheng, DKL ^{[1
]}

Ng, TR ^{[1
]}

Wong, LC ^{[1
]}

Ngan, HYS ^{[1
]}

机构：

[1] UNIV HONG KONG,DEPT OBSTET & GYNAECOL,HONG KONG,HONG KONG

来源：

TUMOR BIOLOGY | 1997年 / 18卷 / 04期

关键词：

prognosis; CA125; CA15.3; CA19.9; carcinoembryonic antigen; tissue polypeptide antigen; endometrial cancer;

D O I：

10.1159/000218037

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Serum cancer antigen (CA) 125, CA15.3, CA19.9, carcinoembryonic antigen and tissue polypeptide antigen were analyzed in 100 normal subjects, 47 patients with benign gynaecological diseases and 97 patients with endometrial cancer. The incidence of individual elevated tumour markers (>2SD) was 21.5-30.9% in cancer patients. Elevations of CA125 and CA15.3 were significantly associated with poor prognostic clinical factors. Univariate anaylses showed that elevated CA125, CA15.3 and CA19.9 were significantly associated with shorter survival. In multivariate analyses, CA15.3 was highly significant and had a larger hazard ratio. In conclusion, CA15.3 is a useful marker for the prognosis of patients with endometrial cancer.

引用

页码：241 / 249

页数：9

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