In vivo splicing and functional characterization of Mycobacterium leprae RecA

被引：8

作者：

Frischkorn, K

Springer, B

Böttger, EC

Davis, EO

Colston, MJ

Sander, P

机构：

[1] Med Hsch Hannover, Inst Med Mikrobiol, D-30625 Hannover, Germany

[2] Natl Inst Med Res, Div Mycobacterial Res, London NW7 1AA, England

来源：

JOURNAL OF BACTERIOLOGY | 2000年 / 182卷 / 12期

关键词：

D O I：

10.1128/JB.182.12.3590-3592.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The RecA proteins from Mycobacterium tuberculosis and Mycobacterium leprae contain inteins. In contrast to the M. tuberculosis RecA, the M leprae RecA is not spliced in Escherichia coli, We demonstrate here that M. leprae RecA is functionally spliced in Mycobacterium smegmatis and produces resistance toward DNA-damaging agents and homologous recombination.

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页码：3590 / 3592

页数：3

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