Investigations of different kilovoltage x-ray energy for three-dimensional converging stereotactic radiotherapy system: Monte Carlo simulations with CT data

被引:13
作者
Deloar, Hossain M.
Kunieda, Etsuo [1 ]
Kawase, Takatsugu
Tsunoo, Takanori
Saitoh, Hidetoshi
Ozaki, Masahiro
Saito, Kimiaki
Takagi, Shunji
Sato, Osamu
Fujisaki, Tatsuya
Myojoyama, Atsushi
Sorell, Graham
机构
[1] Keio Univ, Dept Radiol, Tokyo, Japan
[2] Japan Sci & Technol Agcy, CREST, Tokyo, Japan
[3] Tokyo Metropolitan Univ Hlth Sci, Dept Radiol Sci, Tokyo, Japan
[4] Toshiba Med Syst Corp, CT Syst Div, Tokyo, Japan
[5] Japan Atom Energy Agcy, Ctr Promot Computat Sci & Engn, Ibaraki, Japan
[6] Mitsubishi Res Inst, Safety Engn & Technol Dept, Tokyo, Japan
[7] Ibaraki Prefectural Univ Hlth Sci, Dept Radiat Sci, Ibaraki, Japan
[8] Christchurch Hosp, Dept Med Phys & Bioengn, Christchurch, New Zealand
基金
日本科学技术振兴机构;
关键词
D O I
10.1118/1.2361080
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We are investigating three-dimensional converging stereotactic radiotherapy (3DCSRT) with suitable medium-energy x rays as treatment for small lung tumors with better dose homogeneity at the target. A computed tomography (CT) system dedicated for non-coplanar converging radiotherapy was simulated with BEAMnrc (EGS4) Monte-Carlo code for x-ray energy of 147.5, 200, 300, and 500 kilovoltage (kVp). The system was validated by comparing calculated and measured percentage of depth dose in a water phantom for the energy of 120 and 147.5 kVp. A thorax phantom and CT data from lung tumors (< 20 cm(3)) were used to compare dose homogeneities of kVp energies with MV energies of 4, 6, and 10 MV. Three non-coplanar arcs (0 and 25) around the center of the target were employed. The Monte Carlo dose data format was converted to the XiO RTP format to compare dose homogeneity, differential, and integral dose volume histograms of kVp and MV energies. In terms of dose homogeneity and DVHs, dose distributions at the target of all kVp energies with the thorax phantom were better than MV energies, with mean dose absorption at the ribs (human data) of 100%, 85%, 50%, 30% for 147.5, 200, 300, and 500 kVp, respectively. Considering dose distributions and reduction of the enhanced dose absorption at the ribs, a minimum of 500 kVp is suitable for the lung kVp 3DCSRT system. (c) 2006 American Association of Physicists in Medicine.
引用
收藏
页码:4635 / 4642
页数:8
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