Analysis of cephalosporins in bronchial secretions by capillary electrophoresis after simple pretreatment

被引：30

作者：

Andrasi, Melinda

Gaspar, Attila

Klekner, Almos

机构：

[1] Univ Debrecen, Dept Inorgan & Analyt Chem, H-4010 Debrecen, Hungary

[2] Univ Debrecen, Dept Neurosurg, H-4012 Debrecen, Hungary

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2007年 / 846卷 / 1-2期

关键词：

cephalosporins; capillary electrophoresis; bronchial secretion;

D O I：

10.1016/j.jchromb.2006.08.025

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The applicability of capillary zone electrophoresis (CZE) for analysis of cephalosporin antibiotics has been studied in bronchial secretion as highly viscous, thick and non-homogeneous samples. The lyophilization was found to be a simple but effective pretreatment of these samples to bring them into a form which is suitable for injection to CE capillary. The obtained good recovery data prove that the lyophilization/dissolution of bronchial secretion samples can be reproducibly performed. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：355 / 358

页数：4

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