Mortality in the catastrophic antiphospholipid syndrome:: Causes of death and prognostic factors

被引：64

作者：

Bucciarelli, Silvia ^{[1
]}

Cervera, Ricard ^{[1
]}

Espinosa, Gerard ^{[1
]}

Gomez-Puerta, Jose A. ^{[1
]}

Ramos-Casals, Manuel ^{[1
]}

Font, Josep ^{[1
]}

机构：

[1] Hosp Clin Barcelona, Serv Malalties Autoimmunes, Dept Autoimmune Dis, Inst Clin Med & Dermatol, E-08036 Barcelona, Spain

来源：

AUTOIMMUNITY REVIEWS | 2006年 / 6卷 / 02期

关键词：

D O I：

10.1016/j.autrev.2006.06.007

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In order to know the causes of death and the prognostic factors, our group analyzed 250 patients included until February 2005 in the web-site based international registry of patients with catastrophic antiphosphopholipid syndrome (APS) ("CAPS Registry") (http://www.med.ub.es/MIMMUN/FORUM/CAPS.HTM). Cerebral involvement, mainly consisting of stroke, followed by cardiac involvement and infections were considered the main causes of death in patients with catastrophic APS. The presence of systemic lupus erythematosus was related with higher mortality. According to the results of this analysis, anticoagulation plus steroids plus plasma exchange should be the first line of therapy in patients with catastrophic APS. (c) 2006 Elsevier B.V. All rights reserved.

引用

页码：72 / 75

页数：4

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